DALLAS–(BUSINESS WIRE)–Lantern Pharma Inc. (NASDAQ: LTRN), a medical stage biopharmaceutical firm utilizing its proprietary RADR® synthetic intelligence (“A.I.”) and machine studying (“M.L.”) platform to rework the fee, tempo, and timeline of oncology drug discovery and growth, right this moment introduced that it’ll current preclinical knowledge on the efficiency of Lantern’s drug candidate LP-284 for mantle cell lymphoma (MCL) and several other different non-Hodgkin’s lymphomas on the Society of Hematologic Oncology (SOHO) Tenth Annual Assembly, Sept. 28 – Oct. 1, 2022, in Houston, TX.
LP-284 is a subsequent technology acylfulvene that has a synthetically deadly mechanism of motion in cancers with impaired DNA injury restore (DDR) pathway genes. In Lantern’s preclinical testing, LP-284 has proven in vitro and in vivo anti-tumor efficiency throughout a variety of non-Hodgkin’s B-cell lymphomas. Of the lymphomas examined up to now, LP-284 had the best efficiency in opposition to quite a few MCL cell traces, together with these which can be immune to the standard-of-care (SOC) brokers Ibrutinib and Bortezomib. Within the US, MCL is estimated to be recognized in round 4,500 sufferers annually and represents an approximate $200 million in annual remedy gross sales.
Lantern’s LP-284 program has been accelerated and de-risked utilizing A.I. insights and organic modeling powered by RADR®. Lantern has been capable of advance LP-284 from preliminary RADR® insights concerning anti-cancer exercise and potential mechanisms of motion in hematological cancers, to number of particular subtypes of lymphomas with superior response, to late stage IND enabling research and preliminary design of first in human medical trials in lower than 2 years. Lantern is planning on an IND submission for LP-284 in Q1 2023 and anticipates launching a Part 1 medical trial in Q2 2023.
Particulars of the poster presentation are listed under and will be discovered on the SOHO web site. A full model of the poster will probably be out there on Lantern’s web site on October 3, 2022.
Title: LP-284 – A Extremely Potent Small Molecule Concentrating on Mantle Cell Lymphoma
Date and Time: September 28, 2022, 5:05pm CT
Poster Quantity: MCL-319
Presenter: Jianli Zhou, Lantern Pharma
About Lantern Pharma
Lantern Pharma (NASDAQ: LTRN) is a clinical-stage oncology-focused biopharmaceutical firm leveraging its proprietary RADR® A.I. and machine studying platform to find biomarker signatures that determine sufferers most probably to answer its pipeline of genomically-targeted therapeutics. Lantern is at the moment creating 4 drug candidates and an ADC program throughout 9 disclosed tumor targets, together with two section 2 packages. By concentrating on medication to sufferers whose genomic profile identifies them as having the best likelihood of benefiting from the drug, Lantern’s method represents the potential to ship best-in-class outcomes.
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Web site: www.lanternpharma.com
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