Advancing regenerative drugs as a CU Boulder biomedical engineer | Biomedical Engineering


Kaitlin Mccreery in the lab.Kaitlin Mccreery (MechEngr MS’20, BioEngr PhD’22) is pushing the frontiers of human cartilage analysis as a biomedical engineering PhD graduate from the College of Colorado Boulder.

Mccreery is among the first college students to earn a PhD from this system, which started at CU Boulder in 2020 to bridge the gaps between science, engineering, and drugs.

“I’m within the area of mechanobiology. It’s all about how cells reply to mechanical cues from their environments and the way these cues have an effect on cell differentiation, stem cell destiny, and in the end tissue structure. There are quite a lot of questions right here that haven’t been answered but,” Mccreery mentioned.

Her analysis is concentrated on the microscopic degree and even smaller – on atomic-level interactions that decide how cells behave and construct tissues.

“It’s troublesome to disentangle the biomechanical and biophysical cues. We need to higher predict issues, however getting trigger and impact decided is nuanced,” she mentioned.

The analysis has vital implications for regenerative drugs, an space of rising significance to humanity.

Mccreery spent her masters and PhD conducting experimental analysis on cells beneath the path of Corey Neu, a professor within the Paul M. Rady Division of Mechanical Engineering. She is continuous in his lab this fall as a postdoctoral affiliate, increasing her investigations into multiscale modeling, utilizing huge knowledge methodologies and supercomputers for biomedical analysis.

“There’s a large repository of knowledge obtainable that’s underutilized. Anybody funded by the Nationwide Institutes of Well being has to add their knowledge to authorities servers for anybody to make use of. Much more medical breakthroughs might occur by integrating these massive datasets. It’s a brand new frontier,” Mccreery mentioned.

Constructing a profession in biomedicine is the fruits of long-held aspirations for Mccreery, who has been all in favour of science since childhood.

“I’ve all the time wished to be a scientist,” she mentioned. “I did a mission in center faculty learning a fungus affecting amphibians in my hometown. I received actually into analysis.”

It was maybe an unlikely drive for Mccreery, who grew up in a family with a powerful arts emphasis – her father is an expert cellist, her mom an expert violinist – however her dad and mom inspired her pursuits.

“For generations, folks in my household have been musicians. I’m form of the black sheep. Everybody else is in performing arts,” Mccreery mentioned.

A North Carolina native, Mccreery enrolled at Duke College for her bachelor’s, incomes a level in physics. She was drawn to CU Boulder for her graduate training partially by the college’s collaborative tradition.

“CU Boulder has a extremely nice cooperative analysis setting. I’ve labored in many alternative labs throughout my time right here. There’s leading edge analysis taking place, however folks aren’t aggressive about it. Science can’t occur in a bubble. To be a superb engineer is to be a wonderful teammate,” she mentioned.

Mccreery’ hopes to proceed a profession in analysis long run and subsequent yr will start a place with the Max Planck Institute of Molecular Biomedicine in Münster, Germany. There, she will likely be learning stem cell mechanobiology and chromatin mechanics utilizing superior microscopy and computational strategies.

“That is mission-driven biomedical analysis,” Mccreery mentioned. “I really feel like the world I’m working in has the best want.”



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